Astec CHIROBIOTIC^® T2, like CHIROBIOTIC^® T, is based on bonding the amphoteric glycopeptide Teicoplanin to high-purity silica gel through multiple covalent linkages. Teicoplanin contains 23 chiral centers surrounding four pockets or cavities. It has complementary stereoselectivity to CHIROBIOTIC^® V, R, and T. Important changes in linkage chemistry and the silica have led to enhanced selectivity in the polar organic mode and polar ionic modes, and capacity increases of 2- to 20-fold over the CHIROBIOTIC^® T. Neutral compounds can often be run in pure methanol, and selectivity for basic compounds is excellent.
Bonded phase: Teicoplanin
Operating pH range: 3.8 - 6.8
Particle support: High-purity silica gel
Particle diameter: 5, 10, or 16μm
Pore size: 200 ?
USP Code: L63