LARIHC CF6-P Chiral Columns

This new chiral stationary phase (CSP) was developed as an alkyl derivatized cyclofructan 6 chiral stationary phase. It has demonstrated pronounced enantioselectivity toward all types of primary amines, such as amino alcohols, amino esters, and amino amides. Baseline separation was achieved for simple aliphatic racemic amines that contained no other functionality. Unlike all current crown ether chiral stationary phases, this new column works more effectively with organic solvents and supercritical fluids. It also appears to have great capabilities for preparative-scale separations. No other existing phase can efficiently separate primary amines as well as AZYP’s LARIHC CF6-P phase. A recent study showed that this phase alone can separate 93% of tested racemic primary amines [2]. Additionally, the LARIHC CF6-P phase is broadly selective for many neutral analytes in the normal phase.

LARIHC CF6-M  This phase is currently not available. We recommend the LARIHC CF6-P