克瑞诺拉尼三氟乙酸盐
- 英文名称：Crenolanib Trifluoroacetic Acid Salt
- 价格： ￥99/瓶
- 发布日期： 2019-04-01
- 更新日期： 2025-10-15
产品详请
| 产地 |
加拿大
|
| 品牌 |
进口
|
| 货号 |
03-781800
|
| 英文名称 |
Crenolanib Trifluoroacetic Acid Salt
|
| 包装规格 |
5mg，50mg
|
| 纯度 |
98%
|
| CAS编号 |
|
| 别名 |
1-[2-[5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine Trifluoroacetic Acid Salt; ARO 002 Trifluoroacetic Acid Salt; CP 868596 Trifluoroacetic Acid Salt; [1-[2-[5-(3-Methyloxetan-3-ylmethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-yl]amine Trifluoroacetic Acid Salt;
|
| 分子式 |
C28H30F3N5O4
|
货号：03-781800
中文名称：克瑞诺拉尼三氟乙酸盐
英文名称：p-Cresol-d7
CAS号：
重量：5mg
重量：50mg
分子式：C28H30F3N5O4
别名：1-[2-[5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine Trifluoroacetic Acid Salt; ARO 002 Trifluoroacetic Acid Salt; CP 868596 Trifluoroacetic Acid Salt; [1-[2-[5-(3-Methyloxetan-3-ylmethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-yl]amine Trifluoroacetic Acid Salt;
应用介绍：Crenolanib (CP-868569) is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRα and PDGFRβ. Crenolanib (CP-868569) inhibits the activity of PDGFRα D842V kinase and prevented the phosphorylation of wild type PDGFRα. Crenolanib (CP-868569) possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation.
