4-[（1e，3s，5z，8r/s，10s）-3,11-双[叔丁基（二甲基）硅烷基]氧-2,6,10-三甲基-undeca-1,5-二烯基]-2-甲基-1,3-噻唑
- 英文名称：4-[(1E,3S,5Z,8R/S,10S)-3,11-Bis-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-undeca-1,5-dienyl]-2-methyl-1,3-thiazole
- 价格： ￥99/瓶
- 发布日期： 2019-04-01
- 更新日期： 2025-10-15
产品详请
| 产地 |
加拿大
|
| 品牌 |
进口
|
| 货号 |
02-415890
|
| 包装规格 |
250mg，2.5g
|
| 纯度 |
98%
|
| CAS编号 |
210690-85-0
|
| 别名 |
4-[(1E,3S,5Z,10S)-3,11-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6,10-trimethyl-1,5-undecadien-1-yl]-2-methyl-thiazole;
|
货号：02-415890
中文名称：4-[（1e，3s，5z，8r/s，10s）-3,11-双[叔丁基（二甲基）硅烷基]氧-2,6,10-三甲基-undeca-1,5-二烯基]-2-甲基-1,3-噻唑
英文名称：(R)-O,O-Bis(tert-butyldimethlsilyl) Phenylephrine
CAS号：210690-85-0
重量：250mg
重量：2.5g
分子式：C30H57NO2SSi2
别名：4-[(1E,3S,5Z,10S)-3,11-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,6,10-trimethyl-1,5-undecadien-1-yl]-2-methyl-thiazole;
应用介绍：An intermediate in the synthesis of Epothilones. Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.
