货号：02-285725
中文名称：4-苄基-2-甲基-1,2,4-噻二唑-3,5-二酮
英文名称：rac N-Benzyl Nebivolol
CAS号：327036-89-5
重量：10mg
重量：100mg
分子式：C10H10N2O2S
别名：GSK-3? Inhibitor I, TDZD-8
应用介绍：Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3? ( IC50 =2nM). Binds to the active site of GSK-3?. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).