货号：01-771726
中文名称：A77 1726
英文名称：A77 1726-d4
CAS号：163451-81-8
重量：10mg
重量：25mg
分子式：C12H9F3N2O2
别名：N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide, LEF-M; Teriflunomide
应用介绍：A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective than?injectable interferon beta 1a (Rebif®).?