货号：01-726150
中文名称：盐酸磷灰石
英文名称：Apatinib-d8 Hydrochloride
CAS号：1218779-89-5
重量：10mg
重量：100mg
分子式：C24H24ClN5O
别名：N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide; YN968D1 Hydrochloride;
应用介绍：Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.