Astec CHIROBIOTIC^® T is based on bonding the amphoteric glycopeptide teicoplanin to high-purity silica gel through multiple covalent linkages. Teicoplanin contains 23 chiral centers surrounding four pockets or cavities. CHIROBIOTIC^® T has unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ, or cyclic amino acids, N-derivatized amino acids (i.e. FMOC, CBZ, t-BOC) and alpha hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes, and cyclic aromatic and aliphatic amines. One of the major features of CHIROBIOTIC^® T is its "complementary stereoselectivity" to CHIROBIOTIC^® V and CHIROBIOTIC^® R.

Bonded phase: Teicoplanin
Operating pH range: 3.8 - 6.8
Particle support: High-purity silica gel
Particle diameter: 5, 10, or 16μm
Pore size: 100 ?
USP Code: L63